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AOD-9604

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

Product Usage:

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

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AOD-9604

$

159 AUD

Product Info

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Description

  1. Overview

  1. Biochemical Characteristics

  1. Research Applications

  1. Pathway / Mechanistic Context

  1. Form & Analytical Testing

  1. RUO Disclaimer

  1. Overview

  1. Biochemical Characteristics

  1. Research Applications

  1. Pathway / Mechanistic Context

  1. Form & Analytical Testing

  1. RUO Disclaimer

Overview

FOXO4 DRI is a synthetic peptide derivative investigated in laboratory research for its role in senescent cell biology, apoptosis signalling, and transcription factor related mechanisms. It is commonly utilised in controlled experimental settings focused on FOXO4 associated pathways, p53 localisation, cellular senescence, and peptide based intervention studies. FOXO4 DRI is supplied strictly for research purposes only and is not intended for human or veterinary use.

Overview

FOXO4 DRI is a synthetic peptide derivative investigated in laboratory research for its role in senescent cell biology, apoptosis signalling, and transcription factor related mechanisms. It is commonly utilised in controlled experimental settings focused on FOXO4 associated pathways, p53 localisation, cellular senescence, and peptide based intervention studies. FOXO4 DRI is supplied strictly for research purposes only and is not intended for human or veterinary use.

Biochemical Characteristics

FOXO4 DRI is an all D enantiomer retro inverso peptide designed to interfere with FOXO4 mediated protein interactions involved in senescent cell survival. It is studied as a peptide tool for disrupting the FOXO4 p53 axis, thereby altering nuclear retention of p53 in senescent cells and promoting apoptosis related responses in experimental models. As a synthetic research peptide, FOXO4 DRI is typically handled under controlled laboratory conditions, with stability and storage requirements dependent on formulation, concentration, and preparation method. FOXO4 related signalling is linked to oxidative stress, cell cycle regulation, apoptosis, and longevity associated pathways, making FOXO4 DRI relevant in mechanistic ageing and senescence research.

Biochemical Characteristics

FOXO4 DRI is an all D enantiomer retro inverso peptide designed to interfere with FOXO4 mediated protein interactions involved in senescent cell survival. It is studied as a peptide tool for disrupting the FOXO4 p53 axis, thereby altering nuclear retention of p53 in senescent cells and promoting apoptosis related responses in experimental models. As a synthetic research peptide, FOXO4 DRI is typically handled under controlled laboratory conditions, with stability and storage requirements dependent on formulation, concentration, and preparation method. FOXO4 related signalling is linked to oxidative stress, cell cycle regulation, apoptosis, and longevity associated pathways, making FOXO4 DRI relevant in mechanistic ageing and senescence research.

Research Applications

Senescence Research Investigation of selective targeting of senescent cells and the molecular features that distinguish them from non senescent cells. FOXO4 p53 Interaction Studies Assessment of peptide mediated disruption of FOXO4 p53 binding and its effect on p53 localisation and activity. Apoptosis Mechanism Research Evaluation of apoptosis induction in senescent cell populations under controlled experimental conditions. Ageing Biology Studies Investigation of pathways associated with tissue ageing, cellular damage accumulation, and senescence linked dysfunction. Fibrosis and Tissue Response Research Assessment of senescence associated fibroblast behaviour and extracellular matrix related responses in preclinical models. Endocrine and Regenerative Studies Exploration of senescence linked changes in tissue maintenance, regenerative signalling, and age related cellular decline. Peptide Optimisation Research Comparative evaluation of FOXO4 based senolytic peptide performance, structure activity relationships, and mechanistic efficiency.

Research Applications

Senescence Research Investigation of selective targeting of senescent cells and the molecular features that distinguish them from non senescent cells. FOXO4 p53 Interaction Studies Assessment of peptide mediated disruption of FOXO4 p53 binding and its effect on p53 localisation and activity. Apoptosis Mechanism Research Evaluation of apoptosis induction in senescent cell populations under controlled experimental conditions. Ageing Biology Studies Investigation of pathways associated with tissue ageing, cellular damage accumulation, and senescence linked dysfunction. Fibrosis and Tissue Response Research Assessment of senescence associated fibroblast behaviour and extracellular matrix related responses in preclinical models. Endocrine and Regenerative Studies Exploration of senescence linked changes in tissue maintenance, regenerative signalling, and age related cellular decline. Peptide Optimisation Research Comparative evaluation of FOXO4 based senolytic peptide performance, structure activity relationships, and mechanistic efficiency.

Pathway / Mechanistic Context

FOXO4 Related Senescent Cell Survival FOXO4 is elevated in senescent cells and contributes to maintenance of their viability through interaction with p53. Disruption of FOXO4 p53 Binding FOXO4 DRI is studied as a competing peptide that interferes with this interaction, altering the intracellular behaviour of p53. p53 Nuclear Exclusion and Apoptosis By disrupting FOXO4 mediated retention of p53, the peptide has been described as promoting apoptotic elimination of senescent cells in research models. Senolytic Mechanistic Interest This mechanism has made FOXO4 DRI a notable experimental tool in senolytic research focused on selective clearance of senescent cells. Age Related Pathway Relevance Senescent cell accumulation is associated with tissue dysfunction, fibrosis, and ageing related phenotypes, which is why FOXO4 DRI has been explored in multiple age associated research contexts.

Pathway / Mechanistic Context

FOXO4 Related Senescent Cell Survival FOXO4 is elevated in senescent cells and contributes to maintenance of their viability through interaction with p53. Disruption of FOXO4 p53 Binding FOXO4 DRI is studied as a competing peptide that interferes with this interaction, altering the intracellular behaviour of p53. p53 Nuclear Exclusion and Apoptosis By disrupting FOXO4 mediated retention of p53, the peptide has been described as promoting apoptotic elimination of senescent cells in research models. Senolytic Mechanistic Interest This mechanism has made FOXO4 DRI a notable experimental tool in senolytic research focused on selective clearance of senescent cells. Age Related Pathway Relevance Senescent cell accumulation is associated with tissue dysfunction, fibrosis, and ageing related phenotypes, which is why FOXO4 DRI has been explored in multiple age associated research contexts.

Preclinical Research Summary

FOXO4 DRI is generally supplied as a synthetic research peptide, commonly in lyophilised form, with analytical characterisation typically based on standard peptide quality control methods such as purity profiling and identity confirmation. Products labelled as 10 mg refer to peptide mass rather than biological activity units. In published and reference material, FOXO4 DRI is primarily discussed as a senolytic research compound, with ongoing interest in its activity, stability, and comparative potency relative to newer senescence targeting peptides. Storage, reconstitution, and handling requirements depend on the exact research grade formulation and supplier specifications.

Preclinical Research Summary

FOXO4 DRI is generally supplied as a synthetic research peptide, commonly in lyophilised form, with analytical characterisation typically based on standard peptide quality control methods such as purity profiling and identity confirmation. Products labelled as 10 mg refer to peptide mass rather than biological activity units. In published and reference material, FOXO4 DRI is primarily discussed as a senolytic research compound, with ongoing interest in its activity, stability, and comparative potency relative to newer senescence targeting peptides. Storage, reconstitution, and handling requirements depend on the exact research grade formulation and supplier specifications.

RUO Disclaimer

RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human or animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.

RUO Disclaimer

RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human or animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.

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© Standard BioLabs. All rights reserved.

All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.

Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.

We are committed to supporting all research customers with consistent standards and professional care.

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All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.

Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.

© Standard BioLabs. All rights reserved.

We are committed to supporting all research customers with consistent standards and professional care.

DMCA.com Protection Status

Subscribe

Subscribe to stay updated at every moment about all our news and product drops.

Terms of Service

Refund Policy

Privacy Policy

Promotional Terms

© Standard BioLabs. All rights reserved.

All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.

Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.