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Biochemicals

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SELANK

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

Product Usage:

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.

11 mg

SELANK

$

169 AUD

Product Info

Selank is a synthetic peptide analogue of the naturally occurring immunomodulatory peptide tuftsin, commonly used in laboratory research to study neuropeptide regulation, stress response, and cognitive function. It is of interest in controlled experimental settings examining neurotransmission, anxiety-related pathways, and peptide–receptor interactions. Selank is supplied strictly for research purposes only and is not intended for human or veterinary use.

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Description

  1. Overview

  1. Biochemical Characteristics

  1. Research Applications

  1. Pathway / Mechanistic Context

  1. Form & Analytical Testing

  1. RUO Disclaimer

  1. Overview

  1. Biochemical Characteristics

  1. Research Applications

  1. Pathway / Mechanistic Context

  1. Form & Analytical Testing

  1. RUO Disclaimer

Overview

Selank is a synthetic hexapeptide (Thr-Lys-Pro-Arg-Pro-Gly) derived from thymosin alpha-1 sequence, designed as an anxiolytic and immunomodulatory agent. The peptide is a tuftsin analog that targets immune cells and central nervous system tissues to modulate stress response and immune function. Selank is extensively studied for its potential in reducing anxiety, supporting stress resilience, and enhancing immune competence. Research indicates the peptide promotes anti-anxiety effects through central monoamine modulation while simultaneously enhancing immune cell function and cytokine production. Selank represents a valuable research tool for investigating anxiety disorders, stress adaptation, neuroimmunology, and therapeutic approaches to anxiety and immune dysfunction.

Overview

Selank is a synthetic hexapeptide (Thr-Lys-Pro-Arg-Pro-Gly) derived from thymosin alpha-1 sequence, designed as an anxiolytic and immunomodulatory agent. The peptide is a tuftsin analog that targets immune cells and central nervous system tissues to modulate stress response and immune function. Selank is extensively studied for its potential in reducing anxiety, supporting stress resilience, and enhancing immune competence. Research indicates the peptide promotes anti-anxiety effects through central monoamine modulation while simultaneously enhancing immune cell function and cytokine production. Selank represents a valuable research tool for investigating anxiety disorders, stress adaptation, neuroimmunology, and therapeutic approaches to anxiety and immune dysfunction.

Biochemical Characteristics

Selank is a 6-amino acid peptide with molecular weight of approximately 753 Da. The peptide sequence contains both hydrophobic and charged amino acids enabling multiple receptor interactions in central and peripheral nervous systems. The peptide is water-soluble and crosses the blood-brain barrier efficiently, localizing to central nervous system tissues involved in mood and stress regulation. Selank demonstrates stability across physiological pH ranges (6.5–8.0) and resists enzymatic degradation, supporting extended biological half-life. Cellular uptake occurs through receptor-mediated mechanisms and peptide transporter pathways. The peptide localizes to hippocampus, amygdala, prefrontal cortex, and immune tissues where anxiolytic and immunomodulatory effects are exerted.

Biochemical Characteristics

Selank is a 6-amino acid peptide with molecular weight of approximately 753 Da. The peptide sequence contains both hydrophobic and charged amino acids enabling multiple receptor interactions in central and peripheral nervous systems. The peptide is water-soluble and crosses the blood-brain barrier efficiently, localizing to central nervous system tissues involved in mood and stress regulation. Selank demonstrates stability across physiological pH ranges (6.5–8.0) and resists enzymatic degradation, supporting extended biological half-life. Cellular uptake occurs through receptor-mediated mechanisms and peptide transporter pathways. The peptide localizes to hippocampus, amygdala, prefrontal cortex, and immune tissues where anxiolytic and immunomodulatory effects are exerted.

Research Applications

Anxiety Reduction Investigation of selank-induced reduction in anxiety behavior and anxious phenotypes in experimental models. Stress Resilience Assessment of enhanced resistance to psychological and physical stress through adaptive mechanisms. Mood Regulation Study of effects on depressive behavior and mood-related parameters. Immune Enhancement Investigation of increased phagocytic activity, cytokine production, and immune cell proliferation. Immunosuppression Recovery Assessment of restoration of immune function following stress-induced immunosuppression. Sleep Quality Study of improvements in sleep architecture and restoration of normal sleep-wake cycles. Neuroimmune Integration Examination of bidirectional communication between nervous and immune systems through peptide signaling.

Research Applications

Anxiety Reduction Investigation of selank-induced reduction in anxiety behavior and anxious phenotypes in experimental models. Stress Resilience Assessment of enhanced resistance to psychological and physical stress through adaptive mechanisms. Mood Regulation Study of effects on depressive behavior and mood-related parameters. Immune Enhancement Investigation of increased phagocytic activity, cytokine production, and immune cell proliferation. Immunosuppression Recovery Assessment of restoration of immune function following stress-induced immunosuppression. Sleep Quality Study of improvements in sleep architecture and restoration of normal sleep-wake cycles. Neuroimmune Integration Examination of bidirectional communication between nervous and immune systems through peptide signaling.

Pathway / Mechanistic Context

Monoamine Enhancement Selank increases dopamine and serotonin availability in prefrontal cortex and limbic regions through modulation of monoamine transporter function and synthesis, producing anxiolytic and mood-enhancing effects. GABAergic Modulation The peptide enhances GABAergic inhibitory tone in amygdala and other anxiety-regulating circuits, reducing excitatory drive and promoting anxiolysis. HPA Axis Modulation Selank reduces hypothalamic-pituitary-adrenal (HPA) axis hyperresponsiveness and excessive glucocorticoid signaling, promoting adaptive rather than maladaptive stress responses. Immune Cell Activation The peptide activates macrophages, neutrophils, and T cells through tuftsin receptor binding, enhancing phagocytosis, cytokine production, and immune cell proliferation. Cytokine Enhancement Selank promotes production of IL-2, IL-6, TNF-α and other pro-inflammatory cytokines necessary for effective immune responses and immune cell communication. Stress-Induced Immunosuppression Reversal The peptide counteracts stress-induced suppression of immune function, restoring normal immune cell proliferation and cytokine production capacity.

Pathway / Mechanistic Context

Monoamine Enhancement Selank increases dopamine and serotonin availability in prefrontal cortex and limbic regions through modulation of monoamine transporter function and synthesis, producing anxiolytic and mood-enhancing effects. GABAergic Modulation The peptide enhances GABAergic inhibitory tone in amygdala and other anxiety-regulating circuits, reducing excitatory drive and promoting anxiolysis. HPA Axis Modulation Selank reduces hypothalamic-pituitary-adrenal (HPA) axis hyperresponsiveness and excessive glucocorticoid signaling, promoting adaptive rather than maladaptive stress responses. Immune Cell Activation The peptide activates macrophages, neutrophils, and T cells through tuftsin receptor binding, enhancing phagocytosis, cytokine production, and immune cell proliferation. Cytokine Enhancement Selank promotes production of IL-2, IL-6, TNF-α and other pro-inflammatory cytokines necessary for effective immune responses and immune cell communication. Stress-Induced Immunosuppression Reversal The peptide counteracts stress-induced suppression of immune function, restoring normal immune cell proliferation and cytokine production capacity.

Preclinical Research Summary

Selank is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation, amino acid analysis, and microbial sterility/endotoxin testing. Certificate of Analysis provided with each lot.

Preclinical Research Summary

Selank is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation, amino acid analysis, and microbial sterility/endotoxin testing. Certificate of Analysis provided with each lot.

RUO Disclaimer

RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.

RUO Disclaimer

RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.

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© Standard BioLabs. All rights reserved.

All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.

Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.

We are committed to supporting all research customers with consistent standards and professional care.

DMCA.com Protection Status

Subscribe

Subscribe to stay updated at every moment about all our news and product drops.

Terms of Service

Refund Policy

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Promotional Terms

All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.

Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.

© Standard BioLabs. All rights reserved.

We are committed to supporting all research customers with consistent standards and professional care.

DMCA.com Protection Status

Subscribe

Subscribe to stay updated at every moment about all our news and product drops.

Terms of Service

Refund Policy

Privacy Policy

Promotional Terms

© Standard BioLabs. All rights reserved.

All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.

Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.