This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
Product Usage:
This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
TESAMORELIN
$
249 AUD
Product Info
Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) commonly used in laboratory research to study growth hormone secretion, metabolic regulation, and lipid metabolism. It is of interest in controlled experimental settings examining pituitary function, body composition changes, and hypothalamic-pituitary axis signaling. Tesamorelin is supplied strictly for research purposes only and is not intended for human or veterinary use.
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Categories
Bacteriostatic Water
AOD
Cagrilintide
Cagrilintide + Semaglutide
Retatrutide
Semaglutide
Tirzepatide
SLU PP 332
MOTS C
BPC 157
bpc-157-tb-500
Description
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analog consisting of the human GHRH peptide sequence with a hexarelin modification at the N-terminus. The peptide is designed to enhance growth hormone secretion from the pituitary gland. Tesamorelin is extensively studied for its potential in supporting growth hormone production, metabolic health, body composition improvement, and age-related decline in somatotropin secretion. Research indicates the peptide stimulates robust GH release and produces sustained improvements in lean mass and metabolic function. Tesamorelin represents a valuable research tool for investigating growth hormone physiology, metabolic adaptation, and therapeutic approaches to GH deficiency and age-related somatopause.
Overview
Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analog consisting of the human GHRH peptide sequence with a hexarelin modification at the N-terminus. The peptide is designed to enhance growth hormone secretion from the pituitary gland. Tesamorelin is extensively studied for its potential in supporting growth hormone production, metabolic health, body composition improvement, and age-related decline in somatotropin secretion. Research indicates the peptide stimulates robust GH release and produces sustained improvements in lean mass and metabolic function. Tesamorelin represents a valuable research tool for investigating growth hormone physiology, metabolic adaptation, and therapeutic approaches to GH deficiency and age-related somatopause.
Biochemical Characteristics
Tesamorelin is a 44-amino acid peptide with molecular weight of approximately 5,166 Da. The peptide consists of the complete human GHRH sequence (1-44) with a hexarelin modification providing enhanced stability and extended biological half-life compared to native GHRH. The peptide is water-soluble and stable across physiological pH ranges (6.5–8.0). Cellular uptake occurs through receptor-mediated endocytosis via GHRH receptors on somatotroph cells. Tesamorelin exhibits extended biological half-life due to resistance to enzymatic degradation and extended receptor occupancy. The peptide localizes to hypothalamic and pituitary tissue where it activates GHRH receptors to stimulate growth hormone synthesis and secretion.
Biochemical Characteristics
Tesamorelin is a 44-amino acid peptide with molecular weight of approximately 5,166 Da. The peptide consists of the complete human GHRH sequence (1-44) with a hexarelin modification providing enhanced stability and extended biological half-life compared to native GHRH. The peptide is water-soluble and stable across physiological pH ranges (6.5–8.0). Cellular uptake occurs through receptor-mediated endocytosis via GHRH receptors on somatotroph cells. Tesamorelin exhibits extended biological half-life due to resistance to enzymatic degradation and extended receptor occupancy. The peptide localizes to hypothalamic and pituitary tissue where it activates GHRH receptors to stimulate growth hormone synthesis and secretion.
Research Applications
Growth Hormone Secretion Investigation of tesamorelin-induced enhancement of endogenous growth hormone release from somatotroph cells. Lean Mass Development Assessment of GH-dependent increase in muscle protein synthesis and lean body mass accumulation. Metabolic Rate Enhancement Study of improvements in metabolic rate, energy expenditure, and metabolic flexibility. Body Composition Investigation of improvements in lean-to-fat mass ratio and reduction in visceral adiposity. Lipid Metabolism Assessment of GH-dependent improvements in cholesterol profiles and triglyceride levels. Age-Related Somatopause Examination of potential benefits in age-related growth hormone decline and restoration of GH secretion in aging. Bone Density Study of support for bone remodeling and improvement in bone mineral density through GH signaling.
Research Applications
Growth Hormone Secretion Investigation of tesamorelin-induced enhancement of endogenous growth hormone release from somatotroph cells. Lean Mass Development Assessment of GH-dependent increase in muscle protein synthesis and lean body mass accumulation. Metabolic Rate Enhancement Study of improvements in metabolic rate, energy expenditure, and metabolic flexibility. Body Composition Investigation of improvements in lean-to-fat mass ratio and reduction in visceral adiposity. Lipid Metabolism Assessment of GH-dependent improvements in cholesterol profiles and triglyceride levels. Age-Related Somatopause Examination of potential benefits in age-related growth hormone decline and restoration of GH secretion in aging. Bone Density Study of support for bone remodeling and improvement in bone mineral density through GH signaling.
Pathway / Mechanistic Context
GHRH Receptor Activation Tesamorelin activates growth hormone-releasing hormone (GHRH) receptors on anterior pituitary somatotroph cells, triggering cAMP-dependent signaling cascades that enhance growth hormone synthesis and secretion. Growth Hormone Release Enhanced GHRH signaling promotes accumulation of somatotropin in secretory granules and triggers exocytosis, resulting in robust GH release into circulation. IGF-1 Production Growth hormone stimulated by tesamorelin acts on hepatic tissue and peripheral tissues to enhance insulin-like growth factor-1 (IGF-1) production, which mediates many metabolic and anabolic effects of GH. Lipolysis & Fat Mobilization GH released through tesamorelin stimulation enhances lipolysis in adipose tissue through activation of hormone-sensitive lipase, promoting fat mobilization and utilization as metabolic substrate. Protein Synthesis & Anabolism GH and IGF-1 enhance muscle protein synthesis through mTOR pathway activation and myogenic gene expression, supporting lean mass accumulation. Somatostatin Suppression Tesamorelin-induced GH release provides negative feedback that limits somatostatin (growth hormone-inhibiting hormone) secretion, supporting sustained GH secretory capacity.
Pathway / Mechanistic Context
GHRH Receptor Activation Tesamorelin activates growth hormone-releasing hormone (GHRH) receptors on anterior pituitary somatotroph cells, triggering cAMP-dependent signaling cascades that enhance growth hormone synthesis and secretion. Growth Hormone Release Enhanced GHRH signaling promotes accumulation of somatotropin in secretory granules and triggers exocytosis, resulting in robust GH release into circulation. IGF-1 Production Growth hormone stimulated by tesamorelin acts on hepatic tissue and peripheral tissues to enhance insulin-like growth factor-1 (IGF-1) production, which mediates many metabolic and anabolic effects of GH. Lipolysis & Fat Mobilization GH released through tesamorelin stimulation enhances lipolysis in adipose tissue through activation of hormone-sensitive lipase, promoting fat mobilization and utilization as metabolic substrate. Protein Synthesis & Anabolism GH and IGF-1 enhance muscle protein synthesis through mTOR pathway activation and myogenic gene expression, supporting lean mass accumulation. Somatostatin Suppression Tesamorelin-induced GH release provides negative feedback that limits somatostatin (growth hormone-inhibiting hormone) secretion, supporting sustained GH secretory capacity.
Preclinical Research Summary
Tesamorelin is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation, amino acid analysis, and microbial sterility/endotoxin testing. Bioassay verification of GH-stimulatory activity available upon request. Certificate of Analysis provided with each lot.
Preclinical Research Summary
Tesamorelin is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation, amino acid analysis, and microbial sterility/endotoxin testing. Bioassay verification of GH-stimulatory activity available upon request. Certificate of Analysis provided with each lot.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
We are committed to supporting all research customers with consistent standards and professional care.
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© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
© Standard BioLabs. All rights reserved.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.