EPITALON
$
139 AUD
Product Info
Epitalon is a synthetic tetrapeptide analogue of epithalamin commonly used in laboratory research to study telomerase activity, cellular aging mechanisms, and circadian rhythm regulation. It is of interest in controlled experimental settings examining pineal gland function, melatonin production pathways, and peptide effects on cellular longevity. Epitalon is supplied strictly for research purposes only and is not intended for human or veterinary use.
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Description
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
Epitalon is a synthetic tetrapeptide composed of alanine-glutamic acid-aspartic acid-glycine (Ala-Glu-Asp-Gly) originally derived from bovine pineal gland extracts. The peptide is a regulatory peptide that targets telomerase activity and supports cellular aging mechanisms. Epitalon is extensively studied for its potential role in extending cellular lifespan, supporting telomere maintenance, and promoting longevity. Research indicates the peptide may enhance telomerase activity in aging tissues and support immune function and metabolic health. Epitalon has emerged as a key compound in longevity research, with evidence suggesting it may modulate aging-related pathways and support healthspan extension.
Overview
Epitalon is a synthetic tetrapeptide composed of alanine-glutamic acid-aspartic acid-glycine (Ala-Glu-Asp-Gly) originally derived from bovine pineal gland extracts. The peptide is a regulatory peptide that targets telomerase activity and supports cellular aging mechanisms. Epitalon is extensively studied for its potential role in extending cellular lifespan, supporting telomere maintenance, and promoting longevity. Research indicates the peptide may enhance telomerase activity in aging tissues and support immune function and metabolic health. Epitalon has emerged as a key compound in longevity research, with evidence suggesting it may modulate aging-related pathways and support healthspan extension.
Biochemical Characteristics
Epitalon is a tetrapeptide with molecular weight of approximately 390 Da, composed of alanine (hydrophobic), glutamic acid (acidic), aspartic acid (acidic), and glycine (small, flexible). The peptide is water-soluble and stable across physiological pH ranges (6.5–8.0). Cellular uptake occurs through peptide transporter mechanisms and non-specific endocytosis pathways. Epitalon demonstrates resistance to rapid enzymatic degradation, supporting extended biological half-life and sustained cellular effects. The specific amino acid composition enables multiple interactions with telomerase enzyme complexes and regulatory proteins
Biochemical Characteristics
Epitalon is a tetrapeptide with molecular weight of approximately 390 Da, composed of alanine (hydrophobic), glutamic acid (acidic), aspartic acid (acidic), and glycine (small, flexible). The peptide is water-soluble and stable across physiological pH ranges (6.5–8.0). Cellular uptake occurs through peptide transporter mechanisms and non-specific endocytosis pathways. Epitalon demonstrates resistance to rapid enzymatic degradation, supporting extended biological half-life and sustained cellular effects. The specific amino acid composition enables multiple interactions with telomerase enzyme complexes and regulatory proteins
Research Applications
Telomerase Activity Investigation of epitalon-induced enhancement of telomerase enzyme activity and telomere length maintenance in aging cells. Cellular Aging & Senescence Study of delayed cellular senescence and extended replicative lifespan in cultured cells. Immune Function Assessment of enhancement of T cell proliferation, immune competence, and restoration of age-related immune decline. Longevity & Healthspan Examination of potential lifespan extension and improved quality of life in aging models. Metabolic Health Investigation of improvements in glucose metabolism, insulin sensitivity, and mitochondrial function. Bone & Connective Tissue Study of support for bone density and connective tissue integrity in aging organisms. Neurological Function Assessment of cognitive support and potential neuroprotection in age-related cognitive decline.
Research Applications
Telomerase Activity Investigation of epitalon-induced enhancement of telomerase enzyme activity and telomere length maintenance in aging cells. Cellular Aging & Senescence Study of delayed cellular senescence and extended replicative lifespan in cultured cells. Immune Function Assessment of enhancement of T cell proliferation, immune competence, and restoration of age-related immune decline. Longevity & Healthspan Examination of potential lifespan extension and improved quality of life in aging models. Metabolic Health Investigation of improvements in glucose metabolism, insulin sensitivity, and mitochondrial function. Bone & Connective Tissue Study of support for bone density and connective tissue integrity in aging organisms. Neurological Function Assessment of cognitive support and potential neuroprotection in age-related cognitive decline.
Pathway / Mechanistic Context
Telomerase Activation Epitalon stimulates telomerase reverse transcriptase (TERT) activity and assembly of functional telomerase enzyme complexes, enabling telomere length extension in aging cells. Telomere Maintenance By supporting telomerase-dependent telomere synthesis, epitalon reduces telomere shortening rate and delays onset of replicative senescence. Immune Cell Regeneration Epitalon promotes telomerase activation in T cells and other lymphocytes, extending their replicative potential and enhancing immune competence in aged organisms. Pineal Gland Function The peptide enhances pineal gland-dependent melatonin production and circadian rhythm regulation, supporting overall aging-related endocrine function. Mitochondrial Support Epitalon promotes mitochondrial function and energy metabolism through activation of sirtuins and PGC-1α-dependent mitochondrial biogenesis. Antioxidant Defense The peptide enhances expression of antioxidant enzymes including superoxide dismutase and catalase, reducing oxidative stress burden in aging tissues.
Pathway / Mechanistic Context
Telomerase Activation Epitalon stimulates telomerase reverse transcriptase (TERT) activity and assembly of functional telomerase enzyme complexes, enabling telomere length extension in aging cells. Telomere Maintenance By supporting telomerase-dependent telomere synthesis, epitalon reduces telomere shortening rate and delays onset of replicative senescence. Immune Cell Regeneration Epitalon promotes telomerase activation in T cells and other lymphocytes, extending their replicative potential and enhancing immune competence in aged organisms. Pineal Gland Function The peptide enhances pineal gland-dependent melatonin production and circadian rhythm regulation, supporting overall aging-related endocrine function. Mitochondrial Support Epitalon promotes mitochondrial function and energy metabolism through activation of sirtuins and PGC-1α-dependent mitochondrial biogenesis. Antioxidant Defense The peptide enhances expression of antioxidant enzymes including superoxide dismutase and catalase, reducing oxidative stress burden in aging tissues.
Preclinical Research Summary
Epitalon is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation, amino acid analysis, and microbial sterility/endotoxin testing. Certificate of Analysis provided with each lot.
Preclinical Research Summary
Epitalon is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation, amino acid analysis, and microbial sterility/endotoxin testing. Certificate of Analysis provided with each lot.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
We are committed to supporting all research customers with consistent standards and professional care.
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© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
© Standard BioLabs. All rights reserved.