This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
Product Usage:
This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
PT-141
$
149 AUD
Product Info
PT‑141 (Bremelanotide) is a synthetic peptide analogue of alpha-melanocyte-stimulating hormone (α‑MSH) commonly used in laboratory research to study melanocortin receptor activity and sexual behaviour pathways. It is of interest in controlled experimental settings investigating receptor signalling, neuroendocrine mechanisms, and peptide–receptor interactions. PT‑141 is supplied strictly for research purposes only and is not intended for human or veterinary use.
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Categories
Bacteriostatic Water
AOD
Cagrilintide
Cagrilintide + Semaglutide
Retatrutide
Semaglutide
Tirzepatide
SLU PP 332
MOTS C
BPC 157
bpc-157-tb-500
Description
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
PT-141 (bremelanotide) is a synthetic heptapeptide (Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2) derived from the alpha-melanocyte stimulating hormone (α-MSH) molecule, designed to activate melanocortin receptors and enhance sexual function. The peptide targets neural circuits involved in sexual arousal and erectile function. PT-141 is extensively studied for its potential in supporting sexual function, libido, and erectile response in both male and female subjects. Research indicates the peptide activates melanocortin-4 receptor (MC4R) in the hypothalamus and other brain regions involved in sexual motivation and arousal. PT-141 represents a valuable research tool for investigating sexual neurobiology, melanocortin signaling, and therapeutic approaches to sexual dysfunction and erectile disorders.
Overview
PT-141 (bremelanotide) is a synthetic heptapeptide (Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2) derived from the alpha-melanocyte stimulating hormone (α-MSH) molecule, designed to activate melanocortin receptors and enhance sexual function. The peptide targets neural circuits involved in sexual arousal and erectile function. PT-141 is extensively studied for its potential in supporting sexual function, libido, and erectile response in both male and female subjects. Research indicates the peptide activates melanocortin-4 receptor (MC4R) in the hypothalamus and other brain regions involved in sexual motivation and arousal. PT-141 represents a valuable research tool for investigating sexual neurobiology, melanocortin signaling, and therapeutic approaches to sexual dysfunction and erectile disorders.
Biochemical Characteristics
PT-141 is a 7-amino acid cyclic peptide with molecular weight of approximately 1,024 Da. The peptide contains a cyclized backbone structure with a non-natural amino acid (Nle, norleucine) providing enhanced stability and biological activity compared to native α-MSH. The peptide is water-soluble and crosses the blood-brain barrier efficiently, localizing to hypothalamic and limbic brain regions. PT-141 demonstrates excellent stability across physiological pH ranges (6.5–8.0) and resists enzymatic degradation, supporting extended biological activity. Cellular uptake occurs through melanocortin receptor binding and activation. The peptide localizes to sexually dimorphic brain nuclei and neural circuits regulating sexual motivation and erectile function.
Biochemical Characteristics
PT-141 is a 7-amino acid cyclic peptide with molecular weight of approximately 1,024 Da. The peptide contains a cyclized backbone structure with a non-natural amino acid (Nle, norleucine) providing enhanced stability and biological activity compared to native α-MSH. The peptide is water-soluble and crosses the blood-brain barrier efficiently, localizing to hypothalamic and limbic brain regions. PT-141 demonstrates excellent stability across physiological pH ranges (6.5–8.0) and resists enzymatic degradation, supporting extended biological activity. Cellular uptake occurs through melanocortin receptor binding and activation. The peptide localizes to sexually dimorphic brain nuclei and neural circuits regulating sexual motivation and erectile function.
Research Applications
Sexual Function & Arousal Investigation of PT-141-induced enhancement of sexual arousal and sexual motivation in research models. Erectile Function Assessment of improvements in erectile response and penile tumescence in male subjects. Female Sexual Arousal Study of enhancement of genital arousal, lubrication, and sexual satisfaction in female models. Libido & Sexual Desire Investigation of increased sexual motivation and desire through central melanocortin signaling. Sexual Dysfunction Models Assessment of potential therapeutic benefit in erectile dysfunction and reduced sexual function conditions. Melanocortin Biology Study of melanocortin receptor signaling and physiological effects of MC4R activation in central nervous system. Neuroendocrine Integration Examination of melanocortin signaling in regulation of sexual behavior and reproductive function.
Research Applications
Sexual Function & Arousal Investigation of PT-141-induced enhancement of sexual arousal and sexual motivation in research models. Erectile Function Assessment of improvements in erectile response and penile tumescence in male subjects. Female Sexual Arousal Study of enhancement of genital arousal, lubrication, and sexual satisfaction in female models. Libido & Sexual Desire Investigation of increased sexual motivation and desire through central melanocortin signaling. Sexual Dysfunction Models Assessment of potential therapeutic benefit in erectile dysfunction and reduced sexual function conditions. Melanocortin Biology Study of melanocortin receptor signaling and physiological effects of MC4R activation in central nervous system. Neuroendocrine Integration Examination of melanocortin signaling in regulation of sexual behavior and reproductive function.
Pathway / Mechanistic Context
Melanocortin-4 Receptor Activation PT-141 binds and activates melanocortin-4 receptors (MC4R) in the hypothalamus and other brain regions, triggering cAMP-dependent signaling cascades that promote sexual arousal and erectile function. Hypothalamic Sexual Circuits The peptide activates neurons in sexually dimorphic hypothalamic nuclei (medial preoptic area, ventrolateral hypothalamus) that regulate sexual motivation and arousal. Dopamine & Motivational Pathways PT-141-induced MC4R activation enhances dopamine signaling in reward circuits and motivation-regulating pathways, promoting sexual desire and approach behavior. Cavernous Nerve Activation Central PT-141 effects trigger parasympathetic and nitric oxide-dependent signaling in cavernous tissue, promoting vasodilation and erectile response through enhanced penile blood flow. Female Arousal Enhancement The peptide activates MC4R-mediated pathways regulating female genital arousal, lubrication, and sexual satisfaction through both central and peripheral mechanisms. Melanocortin Pathway Synergy PT-141 engages multiple melanocortin isoforms and receptor subtypes beyond MC4R, creating polypharmacological effects on sexual function and reproduction.
Pathway / Mechanistic Context
Melanocortin-4 Receptor Activation PT-141 binds and activates melanocortin-4 receptors (MC4R) in the hypothalamus and other brain regions, triggering cAMP-dependent signaling cascades that promote sexual arousal and erectile function. Hypothalamic Sexual Circuits The peptide activates neurons in sexually dimorphic hypothalamic nuclei (medial preoptic area, ventrolateral hypothalamus) that regulate sexual motivation and arousal. Dopamine & Motivational Pathways PT-141-induced MC4R activation enhances dopamine signaling in reward circuits and motivation-regulating pathways, promoting sexual desire and approach behavior. Cavernous Nerve Activation Central PT-141 effects trigger parasympathetic and nitric oxide-dependent signaling in cavernous tissue, promoting vasodilation and erectile response through enhanced penile blood flow. Female Arousal Enhancement The peptide activates MC4R-mediated pathways regulating female genital arousal, lubrication, and sexual satisfaction through both central and peripheral mechanisms. Melanocortin Pathway Synergy PT-141 engages multiple melanocortin isoforms and receptor subtypes beyond MC4R, creating polypharmacological effects on sexual function and reproduction.
Preclinical Research Summary
PT-141 is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation with cyclic structure verification, amino acid analysis, and microbial sterility/endotoxin testing. Certificate of Analysis provided with each lot.
Preclinical Research Summary
PT-141 is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation with cyclic structure verification, amino acid analysis, and microbial sterility/endotoxin testing. Certificate of Analysis provided with each lot.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
We are committed to supporting all research customers with consistent standards and professional care.
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© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
© Standard BioLabs. All rights reserved.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.