This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
Product Usage:
This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
SEMAX
$
149 AUD
Product Info
Semax is a synthetic peptide analogue of adrenocorticotropic hormone (ACTH) fragments, commonly used in laboratory research to study neuroprotective effects, cognitive function, and neuropeptide signalling. It is of interest in controlled experimental settings examining neurotransmission, stress response pathways, and peptide–receptor interactions. Semax is supplied strictly for research purposes only and is not intended for human or veterinary use.
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Categories
Bacteriostatic Water
AOD
Cagrilintide
Cagrilintide + Semaglutide
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Semaglutide
Tirzepatide
SLU PP 332
MOTS C
BPC 157
bpc-157-tb-500
Description
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the adrenocorticotropic hormone (ACTH) (4-10) fragment. The peptide is a nootropic agent designed to enhance cognitive function, stress resilience, and neuroprotection. Semax is extensively studied for its potential in supporting learning, memory consolidation, attention, and cognitive performance under stress. Research indicates the peptide enhances brain-derived neurotrophic factor (BDNF) production and supports neuroplasticity mechanisms. Semax represents a valuable research tool for investigating cognitive enhancement, stress adaptation, neuroprotection, and potential therapeutic approaches to cognitive impairment and age-related cognitive decline.
Overview
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the adrenocorticotropic hormone (ACTH) (4-10) fragment. The peptide is a nootropic agent designed to enhance cognitive function, stress resilience, and neuroprotection. Semax is extensively studied for its potential in supporting learning, memory consolidation, attention, and cognitive performance under stress. Research indicates the peptide enhances brain-derived neurotrophic factor (BDNF) production and supports neuroplasticity mechanisms. Semax represents a valuable research tool for investigating cognitive enhancement, stress adaptation, neuroprotection, and potential therapeutic approaches to cognitive impairment and age-related cognitive decline.
Biochemical Characteristics
Semax is a 7-amino acid peptide with molecular weight of approximately 952 Da. The peptide sequence contains both hydrophobic and charged amino acids enabling multiple receptor and protein interactions in the central nervous system. The peptide is water-soluble and crosses the blood-brain barrier efficiently, localizing to central nervous system tissues. Semax demonstrates stability across physiological pH ranges and resists enzymatic degradation better than parent ACTH molecule, supporting extended biological half-life. Cellular uptake occurs through receptor-mediated mechanisms and peptide transporter pathways. The peptide localizes to multiple brain regions including hippocampus, prefrontal cortex, and amygdala where cognitive and stress-related functions are regulated.
Biochemical Characteristics
Semax is a 7-amino acid peptide with molecular weight of approximately 952 Da. The peptide sequence contains both hydrophobic and charged amino acids enabling multiple receptor and protein interactions in the central nervous system. The peptide is water-soluble and crosses the blood-brain barrier efficiently, localizing to central nervous system tissues. Semax demonstrates stability across physiological pH ranges and resists enzymatic degradation better than parent ACTH molecule, supporting extended biological half-life. Cellular uptake occurs through receptor-mediated mechanisms and peptide transporter pathways. The peptide localizes to multiple brain regions including hippocampus, prefrontal cortex, and amygdala where cognitive and stress-related functions are regulated.
Research Applications
Learning & Memory Investigation of enhancement of memory consolidation, information retention, and learning capacity in cognitive models. Cognitive Performance Assessment of improvements in attention, focus, processing speed, and executive function. Stress Resilience Study of enhanced resistance to psychological and physical stress through adaptive mechanisms and HPA axis modulation. Neuroprotection Examination of protective effects against excitotoxicity, oxidative stress, and neuroinflammation. Neuroplasticity Investigation of enhancement of synaptic plasticity, dendritic growth, and long-term potentiation (LTP). Age-Related Cognitive Decline Assessment of potential benefits in age-related memory impairment and cognitive dysfunction. Mood & Emotional Regulation Study of effects on mood, anxiety responses, and emotional processing.
Research Applications
Learning & Memory Investigation of enhancement of memory consolidation, information retention, and learning capacity in cognitive models. Cognitive Performance Assessment of improvements in attention, focus, processing speed, and executive function. Stress Resilience Study of enhanced resistance to psychological and physical stress through adaptive mechanisms and HPA axis modulation. Neuroprotection Examination of protective effects against excitotoxicity, oxidative stress, and neuroinflammation. Neuroplasticity Investigation of enhancement of synaptic plasticity, dendritic growth, and long-term potentiation (LTP). Age-Related Cognitive Decline Assessment of potential benefits in age-related memory impairment and cognitive dysfunction. Mood & Emotional Regulation Study of effects on mood, anxiety responses, and emotional processing.
Pathway / Mechanistic Context
BDNF Enhancement Semax enhances brain-derived neurotrophic factor (BDNF) production and signaling through TrkB receptor activation, supporting neuronal survival, growth, and synaptic plasticity. Memory Consolidation The peptide enhances NMDA receptor-dependent long-term potentiation (LTP) in hippocampus, facilitating memory encoding and consolidation through calcium influx and CREB activation. Stress Adaptation Semax modulates hypothalamic-pituitary-adrenal (HPA) axis responsiveness and glucocorticoid signaling, promoting adaptive stress responses while preventing excessive cortisol-mediated damage. Monoamine Enhancement The peptide increases dopamine and norepinephrine availability in prefrontal cortex and other cognitive regions, supporting attention, motivation, and executive function. Neuroprotection Semax suppresses neuroinflammatory cytokine production, reduces glutamate excitotoxicity, and enhances antioxidant defense enzyme expression in brain tissue. Cerebral Blood Flow The peptide enhances cerebral microvascular perfusion and oxygen delivery to neural tissues, supporting metabolic capacity and cognitive performance.
Pathway / Mechanistic Context
BDNF Enhancement Semax enhances brain-derived neurotrophic factor (BDNF) production and signaling through TrkB receptor activation, supporting neuronal survival, growth, and synaptic plasticity. Memory Consolidation The peptide enhances NMDA receptor-dependent long-term potentiation (LTP) in hippocampus, facilitating memory encoding and consolidation through calcium influx and CREB activation. Stress Adaptation Semax modulates hypothalamic-pituitary-adrenal (HPA) axis responsiveness and glucocorticoid signaling, promoting adaptive stress responses while preventing excessive cortisol-mediated damage. Monoamine Enhancement The peptide increases dopamine and norepinephrine availability in prefrontal cortex and other cognitive regions, supporting attention, motivation, and executive function. Neuroprotection Semax suppresses neuroinflammatory cytokine production, reduces glutamate excitotoxicity, and enhances antioxidant defense enzyme expression in brain tissue. Cerebral Blood Flow The peptide enhances cerebral microvascular perfusion and oxygen delivery to neural tissues, supporting metabolic capacity and cognitive performance.
Preclinical Research Summary
Semax is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation, amino acid analysis, and microbial sterility/endotoxin testing. Certificate of Analysis provided with each lot.
Preclinical Research Summary
Semax is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation, amino acid analysis, and microbial sterility/endotoxin testing. Certificate of Analysis provided with each lot.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
We are committed to supporting all research customers with consistent standards and professional care.
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© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
© Standard BioLabs. All rights reserved.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.