This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
Product Usage:
This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
GHRP-6
$
109 AUD
Product Info
GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide commonly used in laboratory research to study growth hormone secretion and ghrelin receptor activity. It is of interest in experimental settings examining endocrine signalling pathways, appetite-related mechanisms, and peptide–receptor interactions. GHRP-6 is typically utilised in controlled research environments focused on hormonal regulation and metabolic signalling. This compound is supplied strictly for research purposes only and is not intended for human or veterinary use.
Buy 3 and save 15%
Buy 5 and save 20%
Categories
Bacteriostatic Water
AOD
Cagrilintide
Cagrilintide + Semaglutide
Retatrutide
Semaglutide
Tirzepatide
SLU PP 332
MOTS C
BPC 157
bpc-157-tb-500
Description
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
GHRP-6 (growth hormone-releasing peptide-6) is a synthetic hexapeptide (His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) designed as a potent growth hormone secretagogue. The peptide is a ghrelin mimetic that activates growth hormone secretagogue receptors on pituitary somatotroph cells to stimulate endogenous growth hormone release. GHRP-6 is extensively studied for its potential in supporting growth hormone production, lean mass development, and metabolic function. Research indicates the peptide stimulates robust GH secretion through dual mechanisms of pituitary GHS-R activation and hypothalamic GHRH pathway enhancement. GHRP-6 represents a valuable research tool for investigating growth hormone physiology, ghrelin signaling, and therapeutic approaches to GH deficiency and age-related metabolic decline.
Overview
GHRP-6 (growth hormone-releasing peptide-6) is a synthetic hexapeptide (His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) designed as a potent growth hormone secretagogue. The peptide is a ghrelin mimetic that activates growth hormone secretagogue receptors on pituitary somatotroph cells to stimulate endogenous growth hormone release. GHRP-6 is extensively studied for its potential in supporting growth hormone production, lean mass development, and metabolic function. Research indicates the peptide stimulates robust GH secretion through dual mechanisms of pituitary GHS-R activation and hypothalamic GHRH pathway enhancement. GHRP-6 represents a valuable research tool for investigating growth hormone physiology, ghrelin signaling, and therapeutic approaches to GH deficiency and age-related metabolic decline.
Biochemical Characteristics
GHRP-6 is a 6-amino acid hexapeptide with molecular weight of approximately 873 Da. The peptide contains D-amino acids providing enhanced metabolic stability and receptor selectivity compared to natural L-amino acid peptides. The peptide is water-soluble and demonstrates excellent stability across physiological pH ranges (6.5–8.0). GHRP-6 exhibits extended biological half-life due to resistance to enzymatic degradation and high binding affinity for growth hormone secretagogue receptors. Cellular uptake occurs through growth hormone secretagogue receptor (GHS-R) binding and internalization on anterior pituitary somatotroph cells. The peptide localizes to pituitary tissue where growth hormone regulation occurs.
Biochemical Characteristics
GHRP-6 is a 6-amino acid hexapeptide with molecular weight of approximately 873 Da. The peptide contains D-amino acids providing enhanced metabolic stability and receptor selectivity compared to natural L-amino acid peptides. The peptide is water-soluble and demonstrates excellent stability across physiological pH ranges (6.5–8.0). GHRP-6 exhibits extended biological half-life due to resistance to enzymatic degradation and high binding affinity for growth hormone secretagogue receptors. Cellular uptake occurs through growth hormone secretagogue receptor (GHS-R) binding and internalization on anterior pituitary somatotroph cells. The peptide localizes to pituitary tissue where growth hormone regulation occurs.
Research Applications
Growth Hormone Stimulation Investigation of GHRP-6-induced enhancement of endogenous growth hormone release and pulsatile secretion. Lean Mass Development Assessment of GH-dependent increase in muscle protein synthesis and lean body mass accumulation. Metabolic Rate Enhancement Study of improvements in metabolic rate, energy expenditure, and metabolic flexibility. Body Composition Improvement Investigation of improvements in lean-to-fat mass ratio and reduction in adiposity. Age-Related GH Decline Assessment of restoration of GH secretion in aging and potential benefits in age-related somatopause. Physical Performance & Recovery Study of improvements in strength, power output, and exercise capacity through GH enhancement. Appetite Stimulation Investigation of ghrelin-mimetic appetite-stimulating effects and food intake enhancement.
Research Applications
Growth Hormone Stimulation Investigation of GHRP-6-induced enhancement of endogenous growth hormone release and pulsatile secretion. Lean Mass Development Assessment of GH-dependent increase in muscle protein synthesis and lean body mass accumulation. Metabolic Rate Enhancement Study of improvements in metabolic rate, energy expenditure, and metabolic flexibility. Body Composition Improvement Investigation of improvements in lean-to-fat mass ratio and reduction in adiposity. Age-Related GH Decline Assessment of restoration of GH secretion in aging and potential benefits in age-related somatopause. Physical Performance & Recovery Study of improvements in strength, power output, and exercise capacity through GH enhancement. Appetite Stimulation Investigation of ghrelin-mimetic appetite-stimulating effects and food intake enhancement.
Pathway / Mechanistic Context
Ghrelin Receptor Activation GHRP-6 binds and activates growth hormone secretagogue receptors (GHS-R) on anterior pituitary somatotroph cells, triggering IP3-dependent calcium mobilization and phospholipase C activation. Direct Pituitary GH Release GHS-R activation on somatotroph cells directly promotes growth hormone synthesis and pulsatile exocytosis into systemic circulation. Hypothalamic GHRH Enhancement GHRP-6 activates hypothalamic neurons that produce growth hormone-releasing hormone (GHRH), synergizing with direct pituitary effects to amplify GH secretion. Somatostatin Suppression The peptide suppresses somatostatin (growth hormone-inhibiting hormone) secretion from hypothalamic neurons, removing inhibitory tone on GH-releasing neurons. IGF-1 Production Growth hormone released through GHRP-6 stimulation acts on hepatic and peripheral tissues to enhance insulin-like growth factor-1 production, mediating metabolic and anabolic effects. Appetite Pathway Activation GHRP-6 activates central ghrelin pathways in the hypothalamus, promoting appetite signaling and feeding behavior through neuropeptide Y and other appetite-regulating circuits.
Pathway / Mechanistic Context
Ghrelin Receptor Activation GHRP-6 binds and activates growth hormone secretagogue receptors (GHS-R) on anterior pituitary somatotroph cells, triggering IP3-dependent calcium mobilization and phospholipase C activation. Direct Pituitary GH Release GHS-R activation on somatotroph cells directly promotes growth hormone synthesis and pulsatile exocytosis into systemic circulation. Hypothalamic GHRH Enhancement GHRP-6 activates hypothalamic neurons that produce growth hormone-releasing hormone (GHRH), synergizing with direct pituitary effects to amplify GH secretion. Somatostatin Suppression The peptide suppresses somatostatin (growth hormone-inhibiting hormone) secretion from hypothalamic neurons, removing inhibitory tone on GH-releasing neurons. IGF-1 Production Growth hormone released through GHRP-6 stimulation acts on hepatic and peripheral tissues to enhance insulin-like growth factor-1 production, mediating metabolic and anabolic effects. Appetite Pathway Activation GHRP-6 activates central ghrelin pathways in the hypothalamus, promoting appetite signaling and feeding behavior through neuropeptide Y and other appetite-regulating circuits.
Preclinical Research Summary
GHRP-6 is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation with D-amino acid verification, amino acid analysis, and microbial sterility/endotoxin testing. Bioassay verification of GHS-R agonist activity and GH-stimulatory effects available upon request. Certificate of Analysis provided with each lot.
Preclinical Research Summary
GHRP-6 is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–10 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation with D-amino acid verification, amino acid analysis, and microbial sterility/endotoxin testing. Bioassay verification of GHS-R agonist activity and GH-stimulatory effects available upon request. Certificate of Analysis provided with each lot.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
© Standard BioLabs. All rights reserved.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.