This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
Product Usage:
This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
VIP10
$
129 AUD
Product Info
VIP10 is a synthetic peptide analogue of vasoactive intestinal peptide (VIP) commonly used in laboratory research to study neuropeptide signaling, vasodilation mechanisms, and neuroendocrine regulation. It is of interest in controlled experimental settings examining G-protein coupled receptor interactions, smooth muscle relaxation pathways, and peptide-mediated cellular responses. VIP10 is supplied strictly for research purposes only and is not intended for human or veterinary use.
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Categories
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AOD
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Semaglutide
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SLU PP 332
MOTS C
BPC 157
bpc-157-tb-500
Description
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
Biochemical Characteristics
Research Applications
Pathway / Mechanistic Context
Form & Analytical Testing
RUO Disclaimer
Overview
VIP10 is a synthetic peptide derived from vasoactive intestinal peptide (VIP) sequence, designed to support immune function, mucosal integrity, and gastrointestinal health. The peptide targets immune cells and epithelial tissue to modulate inflammatory responses and promote tissue repair. VIP10 is studied for its potential role in supporting immune tolerance, reducing chronic inflammation, and enhancing intestinal barrier function. Research indicates the peptide promotes regulatory T cell differentiation and supports mucosal immune homeostasis. VIP10 represents a valuable research tool for investigating immune regulation, gut health, and therapeutic approaches to inflammatory and autoimmune conditions.
Overview
VIP10 is a synthetic peptide derived from vasoactive intestinal peptide (VIP) sequence, designed to support immune function, mucosal integrity, and gastrointestinal health. The peptide targets immune cells and epithelial tissue to modulate inflammatory responses and promote tissue repair. VIP10 is studied for its potential role in supporting immune tolerance, reducing chronic inflammation, and enhancing intestinal barrier function. Research indicates the peptide promotes regulatory T cell differentiation and supports mucosal immune homeostasis. VIP10 represents a valuable research tool for investigating immune regulation, gut health, and therapeutic approaches to inflammatory and autoimmune conditions.
Biochemical Characteristics
VIP10 is a peptide sequence derived from the N-terminal region of vasoactive intestinal peptide, designed for optimal receptor binding and biological activity. The peptide structure enables interaction with VIP receptors and related G-protein coupled receptor systems. The peptide is water-soluble and stable across physiological pH ranges (6.5–8.0). Cellular uptake occurs through receptor-mediated endocytosis and peptide transporter mechanisms. VIP10 exhibits resistance to rapid enzymatic degradation, supporting extended biological half-life and sustained cellular effects. The peptide localizes to immune tissues including gut-associated lymphoid tissue (GALT) and mucosal surfaces, where it exerts its immunomodulatory effects.
Biochemical Characteristics
VIP10 is a peptide sequence derived from the N-terminal region of vasoactive intestinal peptide, designed for optimal receptor binding and biological activity. The peptide structure enables interaction with VIP receptors and related G-protein coupled receptor systems. The peptide is water-soluble and stable across physiological pH ranges (6.5–8.0). Cellular uptake occurs through receptor-mediated endocytosis and peptide transporter mechanisms. VIP10 exhibits resistance to rapid enzymatic degradation, supporting extended biological half-life and sustained cellular effects. The peptide localizes to immune tissues including gut-associated lymphoid tissue (GALT) and mucosal surfaces, where it exerts its immunomodulatory effects.
Research Applications
Immune Tolerance & Regulation Investigation of enhancement of regulatory T cell (Treg) differentiation and expansion through VIP-receptor signaling. Inflammatory Modulation Assessment of reduction in pro-inflammatory cytokine production and promotion of anti-inflammatory responses. Intestinal Barrier Function Study of support for tight junction protein expression and enhancement of epithelial barrier integrity. Mucosal Immunity Investigation of enhancement of mucosal IgA production and support for local immune responses at mucosal surfaces. Autoimmune Disease Models Assessment of potential therapeutic benefit in experimental autoimmune conditions and chronic inflammatory diseases. Wound Healing & Tissue Repair Study of VIP10-induced enhancement of epithelial cell proliferation and tissue regeneration in mucosal tissues. Neuroimmune Integration Investigation of communication between nervous and immune systems through VIP receptor pathways.
Research Applications
Immune Tolerance & Regulation Investigation of enhancement of regulatory T cell (Treg) differentiation and expansion through VIP-receptor signaling. Inflammatory Modulation Assessment of reduction in pro-inflammatory cytokine production and promotion of anti-inflammatory responses. Intestinal Barrier Function Study of support for tight junction protein expression and enhancement of epithelial barrier integrity. Mucosal Immunity Investigation of enhancement of mucosal IgA production and support for local immune responses at mucosal surfaces. Autoimmune Disease Models Assessment of potential therapeutic benefit in experimental autoimmune conditions and chronic inflammatory diseases. Wound Healing & Tissue Repair Study of VIP10-induced enhancement of epithelial cell proliferation and tissue regeneration in mucosal tissues. Neuroimmune Integration Investigation of communication between nervous and immune systems through VIP receptor pathways.
Pathway / Mechanistic Context
VIP Receptor Signaling VIP10 activates VPAC1 and VPAC2 G-protein coupled receptors on immune and epithelial cells, triggering cAMP-dependent signaling cascades that enhance Treg differentiation and anti-inflammatory responses. Regulatory T Cell Expansion The peptide promotes differentiation of naive T cells into FOXP3+ regulatory T cells through activation of cAMP-PKA signaling and upregulation of TGF-β-dependent mechanisms. Cytokine Modulation VIP10 enhances production of anti-inflammatory cytokines (IL-10, TGF-β) while suppressing pro-inflammatory cytokine production (TNF-α, IL-6, IL-17). Tight Junction Support The peptide enhances expression of claudins and occludin through promotion of epithelial cell-derived TGF-β and other barrier-protective factors. IgA Production Enhancement VIP10 promotes class-switch recombination to IgA in B cells and enhances mucosal antibody transport, supporting local mucosal immunity. Epithelial Cell Proliferation The peptide stimulates intestinal epithelial cell proliferation through EGFR and other growth factor receptor activation, supporting mucosal healing and barrier restoration.
Pathway / Mechanistic Context
VIP Receptor Signaling VIP10 activates VPAC1 and VPAC2 G-protein coupled receptors on immune and epithelial cells, triggering cAMP-dependent signaling cascades that enhance Treg differentiation and anti-inflammatory responses. Regulatory T Cell Expansion The peptide promotes differentiation of naive T cells into FOXP3+ regulatory T cells through activation of cAMP-PKA signaling and upregulation of TGF-β-dependent mechanisms. Cytokine Modulation VIP10 enhances production of anti-inflammatory cytokines (IL-10, TGF-β) while suppressing pro-inflammatory cytokine production (TNF-α, IL-6, IL-17). Tight Junction Support The peptide enhances expression of claudins and occludin through promotion of epithelial cell-derived TGF-β and other barrier-protective factors. IgA Production Enhancement VIP10 promotes class-switch recombination to IgA in B cells and enhances mucosal antibody transport, supporting local mucosal immunity. Epithelial Cell Proliferation The peptide stimulates intestinal epithelial cell proliferation through EGFR and other growth factor receptor activation, supporting mucosal healing and barrier restoration.
Preclinical Research Summary
VIP10 is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–5 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation, amino acid analysis, and microbial sterility/endotoxin testing. Certificate of Analysis provided with each lot.
Preclinical Research Summary
VIP10 is supplied as sterile aqueous solution or lyophilized powder at concentrations of 1–5 mg/mL. Storage at 2–8°C; shelf-life 12–24 months for solutions, 24–36 months for lyophilized material. Analytical testing includes HPLC purity verification (≥95%), HPLC-MS molecular confirmation, amino acid analysis, and microbial sterility/endotoxin testing. Certificate of Analysis provided with each lot.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
RUO Disclaimer
RESEARCH USE ONLY (RUO) This product is intended exclusively for laboratory research and is not approved for clinical use or human/animal administration. Not manufactured for pharmaceutical use. Users assume responsibility for suitability determination, proper storage, safety compliance, and regulatory adherence. Institutional approval (IACUC, IRB) may be required. Information provided is for research reference only and does not constitute medical advice or therapeutic claims.
We are committed to supporting all research customers with consistent standards and professional care.
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© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.
© Standard BioLabs. All rights reserved.
We are committed to supporting all research customers with consistent standards and professional care.
Subscribe
Subscribe to stay updated at every moment about all our news and product drops.
Terms of Service
Refund Policy
Privacy Policy
Promotional Terms
© Standard BioLabs. All rights reserved.
All products on this site are designated for Research Use Only and are supplied solely for laboratory, analytical, or scientific research purposes by qualified professionals. Products are not intended for human or animal use, and no diagnostic, therapeutic, or clinical use is intended or implied.
Standard BioLabs is a chemical supplier. Standard BioLabs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Standard BioLabs is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic Act.